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Breast Cancer Surveillance Following Ovarian Cancer in BRCA Mutation Carriers

Writer's picture: Women's Cancer Research FoundationWomen's Cancer Research Foundation

Women with a BRCA 1 or 2 mutation carriers have an increased risk of developing breast cancer and ovarian cancer. However, the incidence of breast after developing ovarian cancer is unknown.


A 2022 multi-institutional retrospective study evaluated patients with a BRCA-associated ovarian cancer who were diagnosed between 1996 and 2016; the patients were followed for an average of 80 months. The results indicated that 184 patients with BRCA-associated ovarian cancer were identified and 18 (10%) patients were later diagnosed with breast cancer with a median follow-up of 48 months. The majority of breast cancers was diagnosed 3 years following an ovarian cancer diagnosis. In summary, ten percent of women developed breast cancer after first being diagnosed with breast cancer.


The incidence of breast cancer following ovarian cancer in BRCA mutation carriers increases over time, and thus, surveillance is recommended, especially considering these patients demonstrate enhanced ovarian cancer survival rates.


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The Women’s Cancer Research Foundation (WCRF) is one of the most active research organizations in the nation. We are dedicated to studying and evaluating novel treatments for women afflicted with breast, ovarian, endometrial, and cervical cancers. The WCRF persistently endeavors to make a difference in women’s lives by offering them hope, strength, and progress.



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ABOUT US 

Since 1985, the physicians and researchers at the WCRF have been at the forefront of pioneering clinical research, aimed at enhancing cure rates among women diagnosed with breast, ovarian, uterine, and cervical cancers. WCRF actively engages in designing, conducting, and disseminating groundbreaking research focused on cutting-edge medical treatments.


Furthermore, WCRF serves as a vital hub for both foundational and applied research, as well as education, pertaining to the latest advancements in the treatment of breast and gynecologic cancers. In addition to conducting and publishing original research, the WCRF, provides valuable clinical information to physicians and patients alike.
 

 

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